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Retatrutide (LY3437943) is Eli Lilly’s groundbreaking investigational triple agonist (GLP-1/GIP/glucagon) designed for superior weight management and metabolic health. Phase 3 trials have shown average weight loss of up to 28.7% (over 70 lbs) at 68 weeks, along with meaningful A1C reductions and improvements in osteoarthritis pain. Delivered once weekly, this next-generation therapy aims to surpass dual agonists like tirzepatide., retatrutide offers hope for patients seeking more effective solutions for obesity and type 2 diabetes.
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